Optimized Synthesis of Indole Carboxylate Metallo-β-Lactamase Inhibitor EBL-3183

Andrei Baran, Jevgenijs Kuzmins, Jevgenijs Kuznecovs, Alistair J M Farley, Tharindi panduwawala, Anete Parkova, Pavel A Donets, Jurgen Brem, Edgars Sūna, christopher J Schofield, Kirill Shubin

Graphical and numerical representations of 1H and 13C{1H} spectra for all synthesized compounds, preliminary optimization experiments, HPLC chromatograms for trans-16 and 2, GC–MS chromatogram for the trans/cis-16′ mixture, and ICP-MS data for the purified compound 2

Date
30.03.2023.
Keywords
Ethers,Hydrocarbons,Mixtures,Molecular structure,Reagents
Hyperlink
https://pubs.acs.org/doi/10.1021/acs.oprd.3c00002?goto=supporting-info