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Publikācija: Bioceramic Hydroxyapatite Granules for Purification of Biotechnological Products

Publication Type Scientific article indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Bioceramic Hydroxyapatite Granules for Purification of Biotechnological Products
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Vitālijs Lakevičs
Jānis Ločs
Dagnija Loča
Valentīna Stepanova
Līga Bērziņa-Cimdiņa
Juris Pelšs
Keywords Adsorption, Bovine Serum Albumin, Granules, Hydroxyapatite Ceramics
Abstract Sorption experiments of bovine serum albumin (BSA) on hydroxyapatite (HAp) ceramic granules, prepared at three temperatures 900°C, 1000°C and 1150°C were performed at room temperature 18,6 °C and phosphate buffer, pH 5,83; 6.38 and 7,39. Thermal treatment contributed to the decrease of bovine serum albumin immobilization indicating that sorption process depended on HAp ceramics specific surface area and pH values of phosphate buffer solution. However, it was confirmed that granule size was also an important parameter for bovine serum albumin adsorption. As a result of these experiments, the most appropriate adsorption conditions and phosphate buffer pH values influence on to BSA sorption were analyzed.
DOI: 10.4028/www.scientific.net/AMR.284-286.1764
Reference Lakevičs, V., Ločs, J., Loča, D., Stepanova, V., Bērziņa-Cimdiņa, L., Pelšs, J. Bioceramic Hydroxyapatite Granules for Purification of Biotechnological Products. Journal of Advanced Materials Research: Materials and Design, 2011, Vol.284-286 , pp.1764-1769. ISSN 1662-8985. Available from: doi:10.4028/www.scientific.net/AMR.284-286.1764
Additional information Citation count:
ID 10784