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Publikācija: Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates

Publication Type Scientific article indexed in ERIH database, in INT1 or INT2 category journals
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates
Field of research 1. Natural sciences
Sub-field of research 1.4 Chemical sciences
Authors Arita Dubņika
Kaspars Veldre
Andris Actiņš
J. Ļeščenko
Keywords Ipidacrine, differential thermal analysis, powder X-ray diffraction, phase transitions.
Abstract Ipidacrine hydrochloride is pharmaceutically active compound that forms variety of crystalline modifications which differs by solvent type and content in crystalline structure. These crystalline forms analyzed by powder x-ray diffraction, differential thermal analysis, thermogravimetry and Karl Fisher titration. Obtained crystalline forms include two monohydrates, two hemihydrates, two anhydrous forms, two non-stoichiometric hydrates and mixed solvates with octanol and water and methanol and water, solvate with chloroform and dimethylformamide.
DOI: 10.2174/2210289201102010021
Hyperlink: http://www.benthamscience.com/open/toprocj/openaccess2.htm 
Reference Dubņika, A., Veldre, K., Actiņš, A., Ļeščenko, J. Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates. The Open Conference Proceedings Journal, 2011, Vol.2, pp.21-27. ISSN 2210-2892. Available from: doi:10.2174/2210289201102010021
ID 11943