Water treatment with electrolysis was performed in an electrolytic cell with special TinO2n-1 ceramic electrodes and Escherichia coli bacteria were used as a model organism for disinfection experiments. In order to clarify the impact of electrolysis process on water treatment, the model solutions containing chloride ions with the initial concentration less than 1 mmol/L were electrolyzed at the conditions (j = 8,3 mA/cm2, pH 7± 0,2, to = 25oC). Viability of the bacteria E. coli was determined by modified DVC and FISH methods. It was determined that, if electrolysis of solutions with different initial concentrations of chloride ions is done, the amount of released chlorine increases with extending the time of electrolysis and the chloride ion concentration. If chloride ions are present in concentration range, which is common in raw water, using TinO2n-1 electrodes in the electrolysis process it can create enough amount active chlorine to kill more than 99% of E. coli within 15 minutes. A practically applicable simple model for prediction of disinfection efficiency with electrolytic cell has been proposed.