Crystal Structure of Methanolsodium Dianemycin — Methanol (1:2), Na(C47H77O14)(CH4O) • 2CH4O

Zeitschrift für Kristallographie - New Crystal Structures 2012
Viktors Kumpiņš, Sergejs Beļakovs, Ērika Bizdēna, Māris Turks

Microorganisms such as bacteria, fungi, and algae produce a plethora of polyketide natural products. Most of these secondary metabolites are biosynthesized in order to protect the producing organism from other species present in the environment. A strain of Streptomyces milbemycinius NRRL 5739 is known for production of several antibacterial and antiparasitic substances or their precursors. We have unexpectedly isolated and recharacterized a natural product Dianemycin. We succeeded to crystallize the aforementioned natural product in the form of its methanol solvate. Dianemycin belongs to the class of carboxyl ionophores that complex the first row metal cations. The peculiarity of the present X-ray structure is sevencoordinated sodium cation.

Keywords
Dianemycin, Streptomyces milbemycinius, X-ray, ionophores, sevencoordinated sodium cation
DOI
10.1524/ncrs.2012.0066
Hyperlink
http://www.degruyter.com/view/j/ncrs.2012.227.issue-2/ncrs.2012.0066/ncrs.2012.0066.xml

Kumpiņš, V., Beļakovs, S., Bizdēna, Ē., Turks, M. Crystal Structure of Methanolsodium Dianemycin — Methanol (1:2), Na(C47H77O14)(CH4O) • 2CH4O. Zeitschrift für Kristallographie - New Crystal Structures, 2012, Vol.227, Iss.2, pp.145-148. ISSN 1433-7266. e-ISSN 2197-4578. Available from: doi:10.1524/ncrs.2012.0066

Publication language
English (en)