Synthesis of Novel N-Propargyl Substituted 1,4-Dihydropyridene Derivatives as Potential Neuroprotective Agents
Balticum Organicum Syntheticum (BOS2012): International Conference on Organic Synthesis: Program and Abstracts
2012
Kārlis Pajuste,
Dainis Kaldre,
Linda Klimaviciusa,
A. Laizane,
M. Vanina,
Baiba Skrivele,
Kintija Birkmane,
Brigita Cekavicus,
Māra Plotniece,
Martins Rucins,
Arkadij Sobolev,
Aiva Plotniece,
Vija Klusa,
Baiba Jansone
Target-directed synthesis is the combination of different moieties is one molecule: pharmacophore propargyl group, cationic moiety and 1,4-dihydropyridine scaffold as a privileged structure.
Keywords
1,4-DHP, neuroprotective agents
Pajuste, K., Kaldre, D., Klimaviciusa, L., Laizane, A., Vanina, M., Skrivele, B., Birkmane, K., Cekavicus, B., Plotniece, M., Rucins, M., Sobolev, A., Plotniece, A., Klusa, V., Jansone, B. Synthesis of Novel N-Propargyl Substituted 1,4-Dihydropyridene Derivatives as Potential Neuroprotective Agents. In: Balticum Organicum Syntheticum (BOS2012): International Conference on Organic Synthesis: Program and Abstracts, Estonia, Tallinn, 1-4 July, 2012. Tallinn: 2012, pp.152-152.
Publication language
English (en)