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Publikācija: Ultrastructural Characteristics of Tissue Response after Implantation of Calcium Phosphate Ceramics in the Mandible of Rabbit

Publication Type Full-text conference paper published in conference proceedings indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Ultrastructural Characteristics of Tissue Response after Implantation of Calcium Phosphate Ceramics in the Mandible of Rabbit
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Vita Zālīte
Valērija Groma
Dmitrijs Jakovļevs
Jānis Ločs
Ģirts Šalms
Keywords β-tricalcium phosphate, hydroxyapatite, ceramics, tissue, porous structure, cell, microstructure
Abstract This study is undertaken in order to explore interaction between calcium phosphate bioceramics and surrounding tissues in the mandible of rabbit. The tissue response was evaluated 6 months after implantation of ceramics. Three kinds of porous bioceramics were studied: hydroxyapatite (HAp) and HAp mixture with β-tricalcium phosphate (95%HAp/5%β-TCP and 80%HAp/20%β-TCP). X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM) were used to characterize porous bioceramic samples. Transmission electron microscopy (TEM), light microscopy and SEM examinations were applied for evaluation of interaction between tissues and bioceramics. The open porosity of obtained samples is in range between 50 to 60%. Pores have not specific form and mainly they are interconnected. The histological studies demonstrated appearance of a thick fibrous collagenous capsule formed around the pure HAp and presented by densely packed fibers and flattened fibrocytes, while addition of b-TCP evidenced highly vascularized adipose tissue.
DOI: 10.1007/978-3-642-34197-7_51
Hyperlink: http://link.springer.com/chapter/10.1007/978-3-642-34197-7_51 
Reference Zālīte, V., Groma, V., Jakovļevs, D., Ločs, J., Šalms, Ģ. Ultrastructural Characteristics of Tissue Response after Implantation of Calcium Phosphate Ceramics in the Mandible of Rabbit. In: IFMBE Proceedings. Vol.38: International Symposium on Biomedical Engineering and Medical Physics, Latvia, Rīga, 10-12 October, 2012. Berlin: Springer Berlin Heidelberg, 2013, pp.194-197. ISBN 978-3-642-34196-0. e-ISBN 978-3-642-34197-7. ISSN 1680-0737. e-ISSN 1433-9277. Available from: doi:10.1007/978-3-642-34197-7_51
Additional information Citation count:
  • Scopus  0
ID 14416