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Publikācija: In vitro and in vivo Examinations for Detection of Minimal Infective Dose for Biomaterials

Publication Type Full-text conference paper published in conference proceedings indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language In vitro and in vivo Examinations for Detection of Minimal Infective Dose for Biomaterials
Field of research 1. Natural sciences
Sub-field of research 1.6 Biological sciences
Authors Aigars Reinis
J. Vētra
Agnese Stunda Zujeva
Līga Bērziņa-Cimdiņa
J. Kroiča
V. Kuzņecova
D. Rostoka
Keywords In vitro and in vivo Examinations for Detection of Minimal Infective Dose for Biomaterials
Abstract The objective of the study is to examine the minimal infective dose of Staphylococcus epidermidis and Pseudomonas aeruginosa on biomaterials in vivo and in vitro. In this research originally synthesized bioactive biomaterials – 4N glass and 4NK glass-ceramics are calcium phosphate with Na2O and Nb2O5 additives with different crystallinity. For microbiological investigation of biomaterialsS.epidermidis strain ATCC 12228, Ps.aeruginosa strain ATCC 27853, 4 rabbit animal models, broth and agar, scanned electron microscope Tescan, Vortex centrifuge, sonicator and histological methods were used. We observed that different biomaterials had various attachments of S.epidermidis and Ps.aeruginosa in laboratory animal models. The minimal infective dose of S.epidermidis for biomaterial 4NK is more than 103 CFU/ml, for biomaterial 4N less than 103 CFU/ml. The minimal infective dose of Ps.aeruginosa for biomaterial 4N and biomaterial 4NK is less than 103 CFU/ml.
DOI: 10.1007/978-3-642-14515-5_305
Hyperlink: http://rd.springer.com/chapter/10.1007/978-3-642-14515-5_305 
Reference Reinis, A., Vētra, J., Stunda-Zujeva, A., Bērziņa-Cimdiņa, L., Kroiča, J., Kuzņecova, V., Rostoka, D. In vitro and in vivo Examinations for Detection of Minimal Infective Dose for Biomaterials. In: IFMBE Proceedings. Vol.31: 6th World Congress of Biomechanics (WCB 2010), Singapore, Singapore, 1-6 August, 2010. Singapore: Springer Berlin Heidelberg, 2010, pp.1204-1207. ISBN 978-3-642-14514-8. e-ISBN 978-3-642-14515-5. Available from: doi:10.1007/978-3-642-14515-5_305
Additional information Citation count:
ID 15067