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Publikācija: "Click" Approach to the Synthesis of 2

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language "Click" Approach to the Synthesis of 2,6-Bis(1,2,3-triazolyl)purine Deoxynucleosides
Field of research 1. Natural sciences
Sub-field of research 1.4 Chemical sciences
Authors Kristers Ozols
Ērika Bizdēna
Keywords Purine nucleosides, Deoxyribonucleosides, "Click" reaction
Abstract Azide-alkyne 1,3-dipolar cycloaddition reaction (click reaction) has been found to be useful in nucleoside, nucleotide and oligonucleotide chemistry. In last years a number of 1,2,3-triazolylnucleoside derivatives have been synthesized and investigated, leading to discovery of substances with antiviral and anticancer activity, enzyme inhibitors, adenosine receptor agonists and antagonists.
Reference Ozols, K., Bizdēna, Ē. "Click" Approach to the Synthesis of 2,6-Bis(1,2,3-triazolyl)purine Deoxynucleosides. In: Material Science and Applied Chemistry: Scientific Journal of Riga Technical University. Vol.27: Materials of the 8th Paul Walden Symposium on Organic Chemistry, Latvia, Rīga, 13-14 May, 2013. Rīga: RTU Press, 2013, pp.87-87. ISSN 1407-7353. e-ISSN 2255-8713.
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ID 16475