Enterprise applications are used to execute business processes. Users usually have some degree of freedom to select a process execution variant most suited for her/his needs. This chapter develops a simulation model for representing adaptive enterprise applications, where adaptation is aimed at discovering the most efficient ways for business process execution. The simulation model uses process execution productivity as the adaptation criterion. The results obtained show that adaptation allows users to identify the most productive ways for process execution and that the most appropriate process execution configuration depends upon process characteristics. The simulation model is to be used to evaluate alternative solutions for improving productivity of enterprise applications.