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Publikācija: Synthesis of Novel Unsymmetrically Substituted 1

Publication Type Scientific article indexed in ERIH database, in INT1 or INT2 category journals
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Synthesis of Novel Unsymmetrically Substituted 1,4-Dihydroisonicotinic Acid and its Derivatives
Field of research 1. Natural sciences
Sub-field of research 1.4 Chemical sciences
Authors Inguna Goba
B. Turovska
Sergejs Beļakovs
Edgars Liepiņš
Keywords
Abstract The synthesis of new unsymmetrically substituted 1,4-dihydroisonicotinic acid bearing cyano and acetyl groups in positions 3 and 5 of the heterocycle has been developed. The methyl, ethoxycarbonylmethyl, and propionyloxymethyl esters of the acid have been obtained. The method of N-alkylation reaction of synthesized 1,4-dihydroisonicotinic acid esters has been elaborated.
Reference Goba, I., Turovska, B., Beļakovs, S., Liepiņš, E. Synthesis of Novel Unsymmetrically Substituted 1,4-Dihydroisonicotinic Acid and its Derivatives. Химия гетероциклических соединений , 2013, 5, pp.778-787. ISSN 0132-6244.
ID 17147