On Differences between Racemic and Enantiomerically Pure Forms of Aziridine-2-carboxamide
ChemInform
2013
Māris Turks,
Inese Rijkure,
Sergejs Beļakovs,
Daina Zicāne,
Viktors Kumpiņš,
Ērika Bizdēna,
A. Meikas,
A. Valkna
A straightforward, reproducible and scalable method for the synthesis of both enantiomers of aziridine-2-carboxamide (Leakadine) is described.
Keywords
aziridine derivatives; diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism); pharmacology, medicinal chemistry, vaccines, serums
DOI
10.1002/chin.201306058
Hyperlink
http://onlinelibrary.wiley.com/doi/10.1002/chin.201306058/abstract
Turks, M., Rijkure, I., Beļakovs, S., Zicāne, D., Kumpiņš, V., Bizdēna, Ē., Meikas, A., Valkna, A. On Differences between Racemic and Enantiomerically Pure Forms of Aziridine-2-carboxamide. ChemInform, 2013, Vol.44, Iss.6, pp.58-58. ISSN 1522-2667. Available from: doi:10.1002/chin.201306058
Publication language
English (en)