The aim of this study was to find out the biointegration of innovative vascular prosthesis, made in Riga Technical University (RTU), in dog‘s abdominal aorta. The research is being performed in Veterinary Medicine Faculty of Latvia University of Agriculture since July 19, 2011 and is still in progress. We used 9 female gender, 1 - 3 years old Beagle dogs in this study. The research is approved by the Latvian Republic Food and Veterinary Service. The study is carried out in the frame of European Social Fund co-financed project 'Establishment of interdisciplinary research groups for a new functional properties of smart textiles development and integrating in innovative products' (ESF Nr. 2009/0198/1DP/1.1.1.2.0./09/APIA/VIAA/148). 5 - 8 mm in diameter and 8 mm to 18 mm in length RTU produced aortic grafts were implanted retroperitoneal in experimental animals. Before the surgery the diameter of abdominal aorta was measured in cross sections, afterwards – cranial and caudal from the prosthesis, as well cross-section diameter of vascular graft was measured. Results are fallowing- aortic prosthesis and abdominal aorta diameter cranial and distal from it has tendency to change in width in postoperative period.