Silica Nanoparticles as a Carrier of Virus-Like Particles for Hepatitis B Vaccine

Science, Technology and Innovation at the Epoch of Happiness of the Powerful State: Abstract of Papers of the International Scientific Conference 2012
Jurijs Dehtjars, Marina Romanova, Anna Kačanovska, Dace Skrastiņa, Regīna Renhofa, Pauls Pumpēns, Aloizijs Patmalnieks

Adherence of hepatitis B virus like particles to silica (SiO2) nanoparticles was explored for immunomodulation purposes by optical absorbance measurements, transmission electron microscopy, fluorescence microscopy and vaccination of Balb/c mice. The results suggested that SiO2 nanoparticles could be considered as a promising material for improving efficiency of vaccines against hepatitis B viral disease.

Keywords
virus like particles, silica, nanoparticles, immunomodulation, optical absorbance, hepatitis

Dehtjars, J., Romanova, M., Kačanovska, A., Skrastiņa, D., Renhofa, R., Pumpēns, P., Patmalnieks, A. Silica Nanoparticles as a Carrier of Virus-Like Particles for Hepatitis B Vaccine. In: Science, Technology and Innovation at the Epoch of Happiness of the Powerful State: Abstract of Papers of the International Scientific Conference, Turkmenistan, Ashgabat, 12-14 June, 2012. Academy of Sciences of Turkmenistan: Ylym Publishing House, 2012, pp.233-234.

Publication language
English (en)