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Publikācija: Silica Nanoparticles as a Carrier of Virus-Like Particles for Hepatitis B Vaccine

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Silica Nanoparticles as a Carrier of Virus-Like Particles for Hepatitis B Vaccine
Field of research 1. Natural sciences
Sub-field of research 1.3 Physical sciences
Authors Jurijs Dehtjars
Marina Romanova
Anna Kačanovska
Dace Skrastiņa
Regīna Renhofa
Pauls Pumpēns
Aloizijs Patmalnieks
Keywords virus like particles, silica, nanoparticles, immunomodulation, optical absorbance, hepatitis
Abstract Adherence of hepatitis B virus like particles to silica (SiO2) nanoparticles was explored for immunomodulation purposes by optical absorbance measurements, transmission electron microscopy, fluorescence microscopy and vaccination of Balb/c mice. The results suggested that SiO2 nanoparticles could be considered as a promising material for improving efficiency of vaccines against hepatitis B viral disease.
Reference Dehtjars, J., Romanova, M., Kačanovska, A., Skrastiņa, D., Renhofa, R., Pumpēns, P., Patmalnieks, A. Silica Nanoparticles as a Carrier of Virus-Like Particles for Hepatitis B Vaccine. In: Science, Technology and Innovation at the Epoch of Happiness of the Powerful State: Abstract of Papers of the International Scientific Conference, Turkmenistan, Ashgabat, 12-14 June, 2012. Academy of Sciences of Turkmenistan: Ylym Publishing House, 2012, pp.233-234.
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ID 18587