Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure α-Tricalcium Phosphate

The 13th International Conference on Global Research and Education "Inter Academia 2014": Digest 2014
Linda Vecbiškena, Kārlis-Agris Gross, Una Riekstiņa, Yang Sung-Wei, Thomas CK Yang

Nano-sized pure α-tricalcium phosphate (α-TCP) fabricated by a novel synthesis approach shows great potential for a faster transformation into calcium-deficient hydroxyapatite (CDHA) than conventionally prepared α-TCP. In this work, amorphous tricalcium phosphate precursors were precipitated and treated with a solvent (water or ethanol), and dried (freeze-dried and oven-dried) before heating between 650 and 800 °C. Nano-sized α-TCP powders were investigated for their phase composition and crystallinity, particle shape and size, reactivity and cellular biocompatibility. Reaction with water showed faster CDHA formation for freeze-dried powder, at 6 hours, compared to ethanol treated powders whereas a higher biocompatibility was found in a pure α-TCP.

Keywords
Amorphous calcium phosphate, α-tricalcium phosphate, calcium-deficient hydroxyapatite, cell response

Vecbiškena, L., Gross, K., Riekstiņa, U., Sung-Wei, Y., CK Yang, T. Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure α-Tricalcium Phosphate. In: The 13th International Conference on Global Research and Education "Inter Academia 2014": Digest, Latvia, Rīga, 10-12 September, 2014. Riga: Riga Technical University, 2014, pp.212-213. ISBN 978-9934-10-583-8.

Publication language
English (en)