The Effect of Electrochemical Deposited Chitosan–Nanostructured Calcium Phosphate Coatings on Titanium
Abstracts of the 55th International Scientific Conference of Riga Technical University 2014
Linda Vecbiškena, Lina Altomare, Roberto Chiesa, Luigi De Nardo

Biomedical coating research focuses on understanding the interaction between implant surface and biological system and the exploitation of this knowledge to design improved interfaces with biological systems [1,2]. The incorporation of inorganic nanofillers of calcium phosphate (CaP), such as hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), in resorbable organic polymers has been shown accelerate in situ the specific interaction with bone cell surface receptors and thus can properly direct cell proliferation and differentiation [2–5]. In this study, we investigated the functionalization of titanium with chitosan and nanostructured CaP via an electrolytic chemical deposition. [1] R.A. Surmenev, M.A. Surmeneva, A.A. Ivanova, Significance of calcium phosphate coatings for the enhancement of new bone osteogenesis – A review. Acta Biomater., 2014, 10, pp. 557-579. [2] H. Hornberger, S. Virtanen, A.R. Boccaccini, Biomedical coatings on magnesium alloys – A review. Acta Biomater., 2014, 8, pp. 2442-2455. [3] L. Pighinelli, M. Kucharska, Chitosan–hydroxyapatite composites. Carbohydr. Polym., 2013, 93, pp. 256-262. [4] J.H. Kang, H.C. Kim, et al., Osteoconductive effect of chitosan/hydroxyapatite composite matrix on rat skull defect. Tissue Eng. Regen. Med., 2011, 8(1), pp. 23-31. [5] S.M. Kuo, S.J. Chang, et al., Guided tissue regeneration with use of β-TCP/chitosan composite membranes. J. Appl. Polym. Sci., 2009, 112, pp. 3127-3134.


Keywords
Hydroxyapatite, tricalcium phosphate, biocomposite coating, cell response, tissue engineering

Vecbiškena, L., Altomare, L., Chiesa, R., De Nardo, L. The Effect of Electrochemical Deposited Chitosan–Nanostructured Calcium Phosphate Coatings on Titanium. In: Abstracts of the 55th International Scientific Conference of Riga Technical University, Latvia, Rīga, 14-17 October, 2014. Riga: RTU Press, 2014, pp.64-64.

Publication language
English (en)
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