Structure Determination of Three Polymorphs of Xylazine from Laboratory Powder Diffraction Data

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 2014
A. Zvirgzdins, Anatolijs Mišņovs, A. Actins

The crystal structures of three xylazine hydrochloride [N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiaz-2-amine hydrochloride] polymorphs A, Z and X have been solved from powder diffraction data and refined using Rietveld refinement. Data were obtained with Cu K[alpha] radiation. All polymorphs were found to have structures with Z' = 1 and Z = 4. All the structures determined contained strong hydrogen bonds between the amino groups and chloride anions. The crystal structures of forms A and X featured [pi]-[pi] stacking interactions.

Keywords
powder diffraction; xylazine hydrochloride; polymorphism
DOI
10.1107/S2052520614001140
Hyperlink
http://scripts.iucr.org/cgi-bin/paper?S2052520614001140

Zvirgzdins, A., Mišņovs, A., Actins, A. Structure Determination of Three Polymorphs of Xylazine from Laboratory Powder Diffraction Data. Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2014, Vol.70, Iss.2, pp.342-346. e-ISSN 2052-5206. Available from: doi:10.1107/S2052520614001140

Publication language
English (en)