Synthesis of Azole Conjugates with Triterpenes of Lupane Series
2015
Uldis Peipiņš,
Sigita Birzniece
Betulin is naturally occuring triterpene found in the outer layer of birck bark. Betulin itself has shown anti-HIV-activity an certain cytotoxicity. On the other hand, azole heterocycles are a well-estiblished pharmacophores, thank to their non-covalent binding with various receptors and enzymes.
Keywords
Betulin, oxidation, triazoles
Peipiņš, U., Birzniece, S. Synthesis of Azole Conjugates with Triterpenes of Lupane Series. Materials Sciences and Applied Chemistry. Vol.31, 2015, pp.52-52. ISSN 1407-7353. e-ISSN 2255-8713.
Publication language
English (en)