RTU Research Information System
Latviešu English

Publikācija: Burr-like

Publication Type Scientific article indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Burr-like, Laser-Made 3D Microscaffolds for Tissue Spheroid Encagement
Field of research 2. Engineering and technology
Sub-field of research 2.6 Medical engineering
Authors Paulis Danilevicius
Rodrigo Rezenda
Frederico Pereira
Alexandros Selimis
Vladimirs Kasjanovs
Pedro Noritomi
Jorge da Silva
Maria Chatzinikolaidou
Maria Farsai
Vladimir Mironov
Keywords novel technological platform, enabling the rapid, laser-based, in situ 3D tissue biofabrication
Abstract The modeling, fabrication, cell loading, and mechanical and in vitro biological testing of biomimetic, interlockable, laser-made, concentric 3D scaffolds are presented. The scaffolds are made by multiphoton polymerization of an organic–inorganic zirconium silicate. Their mechanical properties are theoretically modeled using finite elements analysis and experimentally measured using a MicrosquisherVR . They are subsequently loaded with preosteoblastic cells, which remain live after 24 and 72 h. The interlockable scaffolds have maintained their ability to fuse with tissue spheroids. This work represents a novel technological platform, enabling the rapid, laser-based, in situ 3D tissue biofabrication.
DOI: 10.1116/1.4922646
Hyperlink: http://scitation.aip.org/content/avs/journal/bip/10/2/10.1116/1.4922646 
Reference Danilevicius, P., Rezenda, R., Pereira, F., Selimis, A., Kasjanovs, V., Noritomi, P., da Silva, J., Chatzinikolaidou, M., Farsai, M., Mironov, V. Burr-like, Laser-Made 3D Microscaffolds for Tissue Spheroid Encagement. Biointerphases, 2015, Vol.10, pp.021011-1-021011-11. ISSN 1934-8630. e-ISSN 1559-4106. Available from: doi:10.1116/1.4922646
Additional information Citation count:
ID 21113