RTU Research Information System
Latviešu English

Publikācija: Calcium Phosphate Bone Cements for Local Vancomycin Delivery

Publication Type Scientific article indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Calcium Phosphate Bone Cements for Local Vancomycin Delivery
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Dagnija Loča
Marina Putniņa
Jānis Ločs
Anastasija Smirnova
Zilgma Irbe
Keywords Calcium phosphate cement, PLA, Vancomycin, Microspheres, Drug delivery
Abstract Among calciumphosphate biomaterials, calciumphosphate bone cements (CPCs) have attracted increased attention because of their ability of self-setting in vivo and injectability, opening the new opportunities for minimally invasive surgical procedures. However, any surgical procedure carries potential inflammation and bone infection risks, which could be prevented combining CPC with anti-inflammatory drugs, thus overcoming the disadvantages of systemic antibiotic therapy and controlling the initial burst and total release of active ingredient
DOI: 10.1016/j.msec.2014.12.075
Hyperlink: http://www.sciencedirect.com/science/article/pii/S092849311400873X 
Reference Loča, D., Sokolova, M., Ločs, J., Smirnova, A., Irbe, Z. Calcium Phosphate Bone Cements for Local Vancomycin Delivery. Materials Science and Engineering C, 2015, Vol.49, pp.106-113. ISSN 0928-4931. Available from: doi:10.1016/j.msec.2014.12.075
Additional information Citation count:
ID 21153