Integration of Biphasic Calcium Phosphate Bioceramics Mixed with Autologous Mesenchymal Cells in Osteoporotic Rabbit’s Jaw

27th European Conference on Biomaterials: Final Programme and Book of Abstracts 2015
Aleksandrs Grišuļonoks, Inese Čakstiņa, Arvīds Jakovļevs, Vita Šteinberga, Ilze Šalma, Andrejs Skaģers, Vadims Klimecs

Bone tissue engineering using biphasic calcium phosphate bioceramics as scaffold saturated by autologous mesenchymal cells in autologous enviroinement of host living organism as bioreactor is one challenge for substitution of autologous bone grafting. Role of autologous mesenchymal cells for biologisation of inorganic bone substitutes to improve their osteogenic properties is contradictory between healthy bone and compromised bone and environments. The fate of transplanted mesenchymal cells is discused between new bone formation and early death with release of some osteotrophic growth factors and mediators for cell recruitments remains unknown.

Keywords
Biphasic Calcium Phosphate Bioceramics, Mesenchymal Cells, Granule

Grišuļonoks, A., Čakstiņa, I., Jakovļevs, A., Zālīte, V., Šalma, I., Skaģers, A., Klimecs, V. Integration of Biphasic Calcium Phosphate Bioceramics Mixed with Autologous Mesenchymal Cells in Osteoporotic Rabbit’s Jaw. In: 27th European Conference on Biomaterials: Final Programme and Book of Abstracts, Poland, Krakow, 30 Aug-3 Sep., 2015. Krakow: Scientific Publishing House „Akapit”, 2015, pp.703-703. ISBN 978-83-63663-63-6.

Publication language
English (en)