RTU Research Information System
Latviešu English

Publikācija: Integration of Biphasic Calcium Phosphate Bioceramics Mixed with Autologous Mesenchymal Cells in Osteoporotic Rabbit’s Jaw

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Integration of Biphasic Calcium Phosphate Bioceramics Mixed with Autologous Mesenchymal Cells in Osteoporotic Rabbit’s Jaw
Field of research 3. Medical and Health sciences
Sub-field of research 3.2 Clinical medicine
Authors Aleksandrs Grišuļonoks
Inese Čakstiņa
Arvīds Jakovļevs
Vita Zālīte
Ilze Šalma
Andrejs Skaģers
Vadims Klimecs
Keywords Biphasic Calcium Phosphate Bioceramics, Mesenchymal Cells, Granule
Abstract Bone tissue engineering using biphasic calcium phosphate bioceramics as scaffold saturated by autologous mesenchymal cells in autologous enviroinement of host living organism as bioreactor is one challenge for substitution of autologous bone grafting. Role of autologous mesenchymal cells for biologisation of inorganic bone substitutes to improve their osteogenic properties is contradictory between healthy bone and compromised bone and environments. The fate of transplanted mesenchymal cells is discused between new bone formation and early death with release of some osteotrophic growth factors and mediators for cell recruitments remains unknown.
Reference Grišuļonoks, A., Čakstiņa, I., Jakovļevs, A., Zālīte, V., Šalma, I., Skaģers, A., Klimecs, V. Integration of Biphasic Calcium Phosphate Bioceramics Mixed with Autologous Mesenchymal Cells in Osteoporotic Rabbit’s Jaw. In: 27th European Conference on Biomaterials: Final Programme and Book of Abstracts, Poland, Krakow, 30 Aug-3 Sep., 2015. Krakow: Scientific Publishing House „Akapit”, 2015, pp.703-703. ISBN 978-83-63663-63-6.
Full-text
ID 21170