Comparison of Tandem Quadrupole Mass Spectrometry and Orbitrap High Resolution Mass Spectrometry for Analysis of Pharmaceutical Residues in Biota Samples

Materials Science and Applied Chemistry 2016
Ingars Reinholds, Iveta Pugajeva, Vadims Bartkevičs

This research demonstrates the development of reliable multi-component methods for the detection of antibiotic residues in environmental biota. The efficiency of analytical performance of ultra high performance liquid chromatography (UHPLC) techniques with triple quadrupole (QqQ-MS/MS) and Orbitrap high-resolution mass spectrometry (Orbitrap-HRMS) detectors is discussed. Antibiotic residues in biota samples collected in Latvia were analysed. The contamination status was determined as rather low within acceptable levels set by the European Union Regulations.

Keywords
Antibiotic residues, Orbitrap high resolution mass spectrometry, tandem mass spectrometry, ultra-high performance liquid chromatography
DOI
10.1515/msac-2016-0001

Reinholds, I., Pugajeva, I., Bartkevičs, V. Comparison of Tandem Quadrupole Mass Spectrometry and Orbitrap High Resolution Mass Spectrometry for Analysis of Pharmaceutical Residues in Biota Samples. Materials Science and Applied Chemistry, 2016, 33, pp.5-10. ISSN 1407-7353. e-ISSN 2255-8713. Available from: doi:10.1515/msac-2016-0001

Publication language
English (en)