This article explores the importance of internationalization and valorization in technical Universities as one of core priorities for achieving international excellence and strengthening university – industry collaboration. The World is becoming more interconnected and Higher Education institutions can no more act on their own – they are motivated and even forced to become international. But an important topic for management of each University, especially technical, is to strengthen the collaboration with business in global environment. Valorization or creation of new products and services through innovation process is an important task for all technical Universities that want to maintain strong bond with the industry and capitalize on this process. This article is based on research conducted between technical Universities in Baltic States, where different processes in university internationalization and valorizations have been distinguished as main driving forces of institutional development. The conducted research shows that this task can be achieved by increased international research, student mobility, large scale jointly managed projects and other international activities. After internationalization and valorization processes have been analyzed, establishing the most critical key elements for fostering both of these processes, authors present an evaluation of Riga Technical University’s case as an example on how internal Information Systems provide the possibility for management to both implement strategic settings of the University and accelerate valorization within the University. This can be achieved trough correct strategy development based on key elements of valorization and internationalization, effective strategy implementation, monitoring and creating of appropriate incentive mechanism where IT support pay an important role.