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Publikācija: Development and Characterization of Mg-Containing Hydroxyapatite

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Development and Characterization of Mg-Containing Hydroxyapatite, β-Tricalcium Phosphate and Biphasic Calcium Phosphate Bioceramics
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Līga Stīpniece
Inga Narkevica
Kristīne Šalma-Ancāne
Līga Bērziņa-Cimdiņa
Keywords bioceramic, calcium phosphates, magnesium
Abstract Calcium phosphates (CaPs), e.g. hydroxyapatite, β-tricalcium phosphate due to their unique properties – bioactivity and/or biodegradability, osteoconductivity, are considered to be promising bone grafts. CaPs present themselves as prime materials for modification, aiming for improvements on physicochemical and biological aspects of novel graft. Nowadays interest is turning towards modified synthetic CaPs involving the addition of various elements. The goal of our work is to develop Mg-containing CaP bioceramics and to evaluate an effect of the Mg addition on physicochemical characterization in particle and bulk level, as well as asses a biological performance of the Mg-containing CaP bioceramics. Results confirmed that CaP bioceramics with various and reproducible phase and chemical composition were obtained through the precipitation of precursors followed by uniaxial compaction and sintering (1100 oC, 1 h). The Mg-containing CaP bioceramics show advisable bioactivity with osteogenic progenitor cells and have good cytocompatibility, showing no negative effects on cells growth and proliferation.
Hyperlink: http://mrs-serbia.org.rs/index.php/yucomat-2016-book-of-abstracts 
Reference Stīpniece, L., Narkevica, I., Šalma-Ancāne, K., Bērziņa-Cimdiņa, L. Development and Characterization of Mg-Containing Hydroxyapatite, β-Tricalcium Phosphate and Biphasic Calcium Phosphate Bioceramics. In: Eighteenth Annual Conference YUCOMAT 2016: Programme and the Book of Abstracts, Montenegro, Herceg Novi, 5-10 September, 2016. Herceg Novi: Materials Research Society of Serbia, 2016, pp.93-93. ISBN 978-86-919111-1-9.
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