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Publikācija: 1

Publication Type Full-text conference paper published in other conference proceedings
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language 1,2,3-Triazole Moiety- a Useful Tool for Functionalization of Purine Nucleosides
Field of research 1. Natural sciences
Sub-field of research 1.4 Chemical sciences
Authors Kristers Ozols
Dace Cīrule
Irina Novosjolova
Ērika Bizdēna
Māris Turks
Keywords Purine derivatives, nucleosides, fluorescent nucleosides, adenosine analogues, Click chemistry
Abstract Azide-alkyne 1,3-dipolar cycloaddition has been employed for the preparation of purine 2,6-bis-(1,2,3-triazol-1-yl) derivatives. These compounds are excellent substrates for SNAr reactions and hence have been used to prepare nucleophilic substitution products in good to excellent yields. Some of the obtained products exhibit fluorescent properties.
Hyperlink: https://conferences.rtu.lv/index.php/MSAC/MSAC2016/paper/viewFile/36/20 
Reference Ozols, K., Cīrule, D., Novosjolova, I., Bizdēna, Ē., Turks, M. 1,2,3-Triazole Moiety- a Useful Tool for Functionalization of Purine Nucleosides. In: Riga Technical University 57th International Scientific Conference "Materials Science and Applied Chemistry" (MSAC 2016): Proceedings and Programme, Latvia, Riga, 21-21 October, 2016. Riga: RTU Press, 2016, pp.139-142. ISBN 978-9934-10-861-7.
ID 22882