This work will consider nondestructive Fourier transform infra-red spectroscopy – diffuse reflectance induced reflection (FTIR-DRIFT) for collecting the spectra and deconvolution to identify changes in bonding as a means of more powerful detection. Spectra were recorded from bone samples (obtained in Latvia) and compared with in laboratory synthesized calcium phosphates. FTIR-DRIFT was used to study the chemical environments of PO4, CO3 ions as well as amides and CH2 groups. Deconvolution of spectra separated overlapping bands in the PO4, CO3, and amide region allowing a closer analysis of changes within the material at the ionic and molecular level.