Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond

Balticum Organicum Syntheticum (BOS 2016): Program and Abstract Book 2016
Marija Skvorcova, Aigars Jirgensons

Herein we present directed protolytic cleavage of cyclopropane in cyclopropane containing amides where protonated amide serves as an intramolecular proton donor. The resulting intermediate carbenium ion is trapped with amide nitrogen leading to pyrrolidine derivatives.

Keywords
amide, protonolysis, cyclopropane, pyrrolidine

Skvorcova, M., Jirgensons, A. Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond. In: Balticum Organicum Syntheticum (BOS 2016): Program and Abstract Book, Latvia, Riga, 3-6 July, 2016. Riga: 2016, pp.145-145.

Publication language
English (en)