N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions

Balticum Organicum Syntheticum (BOS 2016): Program and Abstract Book 2016
Elīna Līdumniece, Dace Rasiņa, Aigars Jirgensons

We have discovered that ruthenium(II) catalyzes annulation of N-acylsulfonamides with alkynes producing isoquinolinones. This reaction proceeds with concomitant N–S bond reduction in acylsulfonamide which ensures the ruthenium catalytic cycle without addition of external oxidants.

Keywords
C-H activation, annulation, ruthenium, N-acylsulfonamides

Līdumniece, E., Rasiņa, D., Jirgensons, A. N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions. In: Balticum Organicum Syntheticum (BOS 2016): Program and Abstract Book, Latvia, Riga, 3-6 July, 2016. Riga: 2016, pp.130-130.

Publication language
English (en)