Small Nitrogen Heterocycles Containing 1,2,3-Triazoles in the Side Chain
2015
Krista Gulbe,
Diāna Stamberga,
Andrejs Solops
New libraries of aziridine and azetidine derivatives containing 1,4-disubstituted 1,2,3-triazole in the side chain as well as aziridine derivatives containing 1,5-disubstituted 1,2,3-triazole in the side chain were synthesized by transition metals catalyzed Huisgen 1,3-dipolar cycloaddition. Biological activity of target compounds for inhibition of matrix metalloproteinases will be discussed.
Keywords
New libraries of aziridine and azetidine derivatives containing 1,4-disubstituted 1,2,3-triazole in the side chain as well as aziridine derivatives containing 1,5-disubstituted 1,2,3-triazole in the side chain were synthesized by transition metals catalyzed Huisgen 1,3-dipolar cycloaddition. Biological activity of target compounds for inhibition of matrix metalloproteinases will be discussed.
Suta, K., Stamberga, D., Solops, A. Small Nitrogen Heterocycles Containing 1,2,3-Triazoles in the Side Chain. Materials Sciences and Applied Chemistry. Vol.31, 2015, pp.54-54. ISSN 1407-7353.
Publication language
English (en)