Intramolecular Cyclopropylmethylation via Non-Classical Carbocations

Organic & Biomolecular Chemistry 2017
Marija Skvorcova, Aigars Jirgensons

Cyclopropyl–cyclopropyl rearrangement can be achieved selectively by intramolecular trapping of cyclopropylmethyl carbenium ions with an internal nucleophile. This can be exploited as a useful method for the introduction of a cyclopropyl group into complex molecules using readily accessible disubstituted cyclopropane intermediates.

Keywords
non-classical carbocations, Intramolecular cyclopropylmethylation
DOI
10.1039/C7OB01721A
Hyperlink
http://pubs.rsc.org/en/Content/ArticleLanding/2017/OB/C7OB01721A#!divAbstract

Skvorcova, M., Jirgensons, A. Intramolecular Cyclopropylmethylation via Non-Classical Carbocations. Organic & Biomolecular Chemistry, 2017, Vol.15, pp.6909-6912. ISSN 1477-0520. e-ISSN 1477-0539. Available from: doi:10.1039/C7OB01721A

Publication language
English (en)