This report explores two key manufacturing processes, and assesses multiple parameters for optimization of these processes. High shear dispersion using a rotor-stator style homogenizer and high-energy grinding using a basket type mill with zirconium balls as the grinding media were studied. The variation between grinding organic and inorganic pigments was assessed as they give different challenges and require different operations to produce successful results. Obtaining the correct particle size distribution of pigments for decorative coatings is of paramount importance for achieving a high quality, functioning, aesthetically pleasing finished product. This analysis will explore the de-agglomeration and dispersion of inorganic TiO2 and organic Red 6 pigments using basket milling technology. High energy basket mill grinding produced the smallest particle size and smallest particle size distribution comparing with high shear dispersion. Used technology allowed to achieve inorganic pigment TiO2 particle size and particle size distribution suitable for use in coatings on natural nails. For organic pigment Red 6 used technology should be customized.