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Publikācija: Comparative Study of Surface Properties of Mg-Substituted Hydroxyapatite Bioceramic Microspheres

Publication Type Scientific article indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Comparative Study of Surface Properties of Mg-Substituted Hydroxyapatite Bioceramic Microspheres
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Līga Stīpniece
Valentīna Stepanova
Inga Narkevica
Kristīne Šalma-Ancāne
Adrian R. Boyd
Keywords Hydroxyapatite, Bioceramic, Microspheres, Mg substitution, Protein adsorption
Abstract Mg-substituted hydroxyapatite (HAp) bioceramic microspheres were prepared by spray drying and subsequent processing at 1173, 1273 and 1373 K. Influence of various Mg substitution levels (up to 0.84 ± 0.10 wt%) on physicochemical properties of the HAp bioceramic microspheres was evaluated. Obtained results were used for the elucidation of the compositional and structural characteristics of the microspheres in conjunction with adsorption of protein, namely, bovine serum albumin (BSA). The primary difference among the microspheres processed at various temperature was the presence or absence of the micropores (< 2 nm in diameter) and mesopores (between 2 and 50 nm). Presence of the micro- and mesopores resulted in higher specific surface area (SSA), enhanced solubility, i.e., ion release, and, accordingly, increase in the amount of BSA adsorbed on the microspheres. Furthermore, the BSA adsorption capacity of the microspheres decreased with increasing Mg content despite of higher SSA.
DOI: 10.1016/j.jeurceramsoc.2017.09.026
Hyperlink: http://www.sciencedirect.com/science/article/pii/S0955221917306404?via%3Dihub 
Reference Stīpniece, L., Stepanova, V., Narkevica, I., Šalma-Ancāne, K., Boyd, A. Comparative Study of Surface Properties of Mg-Substituted Hydroxyapatite Bioceramic Microspheres. Journal of the European Ceramic Society, 2018, Vol.38, Iss.2, pp.761-768. ISSN 0955-2219. Available from: doi:10.1016/j.jeurceramsoc.2017.09.026
Additional information Citation count:
ID 26257