Novel Ciprofloxacin Derivatives for Polymer-Based Drug Delivery Systems

Key Engineering Materials 2018
Tatjana Gerasimova, Vitālijs Rjabovs, Māris Turks

Novel derivatives of fluoroquinolone antibiotic ciprofloxacin were synthesized. The modifications of both the N- and C-termini were focused on introduction of functionalized linkers that can be used for covalent attachment to natural or synthetic polymers with appropriate functional groups.

Keywords
ciprofloxacin, α-amino acids, ciprofloxacin peptides, azide alkyne cycloaddition
DOI
10.4028/www.scientific.net/KEM.762.36
Hyperlink
https://www.scientific.net/KEM.762.36

Gerasimova, T., Rjabovs, V., Turks, M. Novel Ciprofloxacin Derivatives for Polymer-Based Drug Delivery Systems. In: Key Engineering Materials, Latvia, Riga, 20-20 October, 2017. Switzerland: Trans Tech Publications, 2018, pp.36-41. ISSN 1662-9795. e-ISSN 1662-9795. Available from: doi:10.4028/www.scientific.net/KEM.762.36

Publication language
English (en)