Glycosylation is one of the most important strategy towards glycosidic bond formation in carbohydrate chemistry. Still, there is no universal conditions for glycosylation reaction. Yield, regio- and stereoselectivity are the main criteria that determinate application limits of known glycosylation methods. Appropriate, even specific, combination of glycosyl donor and its activator, glycosyl acceptor and solvent has to be developed to reach optimal results. Glycosyl halides are widely used glycosyl donors with glycosyl fluorides being the most stable ones. Based on Lewis acid properties of liquid SO2 as well as Eisfeld study on solvation of fluoride ion by this unconventional solvent, we decided to explore glycosylation reaction in liquid SO2 by employing glycosyl fluorides as glycosyl donors.