Peptidic α-ketoamides as PfSUB1 Inhibitors

Balticum Organicum Syntheticum (BOS 2018): Program and Abstracts 2018
Elīna Līdumniece, Aigars Jirgensons

We have developed peptidic PfSUB1 inhibitors containing α-ketoamide warhead. Preliminary SAR investigations revealed the crucial interactions of ketoamide inhibitors. Here we report additional studies to explore the optimal substituents for sub-pockets.

Keywords
PfSUB, inhibitors, α-ketoamide

Līdumniece, E., Jirgensons, A. Peptidic α-ketoamides as PfSUB1 Inhibitors. In: Balticum Organicum Syntheticum (BOS 2018): Program and Abstracts, Tallinn, 1-4 July, 2018. Tallinn: 2018, pp.95-95.

Publication language
English (en)