Creativity and intellectual capital development contribution to city is an important economical component of the modern cities. Due the flexible nature and soft cluster borders, an exact contribution evaluation is burdened, indicating a need for modelling, and still for planning and city development planning a necessary condition is at least qualitative understanding of the economic contribution of particular cluster and consider some models for development analysis as alternative comparison. The competitiveness of the territories depends on their attractiveness to economically active individuals and the opportunities city to provide for resulting economic growth with satisfying needs for qualitative intellectual services. Viewing as intellectual and creativity service portfolio in particular city or a city district (area) can to be analysed for understanding resulting economic activity in city. Authors used literature review and rapid review to assess the challenges of assessing and analysing situation in cities for estimating and modelling culture and creativity cluster contribution for a city economy development. The research results indicate that culture and creativity cluster is providing increasingly growing contribution for modern city economy. The authors suggest to assess culture and creativity cluster contribution with a model and to use the classification according the general economic activity (NACE) (Statistical Classification of Economic Activities in the European Community, Rev. 2, 2017). To verify initial theoretical model analysis in 4 cities was performed and results presented. Even if with generalized model analysis depth is limited, still it can be used to provide necessary basis for decision making, and possible for a particular city identifying as potential areas of focus. More advanced analysis models may improve long term development initiative target achievement rates and to support the planning and later integration of cultural and creative sector activity sources into urban economy. It also would help to assess funding alternatives of investments needed and unified methodology when used for different cities would provide comparable Key Performance Indicators (KPIs) to compare cultural and creative sector contribution to city economies and together with historical data also would provide basis for further model improvements.