The first part of this study is a compiled literature review of microbial and antibacterial activity with textiles. One of the reasons synthetic textiles are prone to gain sweat odor is the usage of lower temperatures and concentrations of detergents during washing. Bacteria that are common in human skin microflora and promote sweat odor are Staphylococcus sp, Bacillus subtilis, Corynebacterium sp, other bacteria and yeast. Microbial growth and chemical absorption or combination of both are the main reasons for malodor formation1. A sol-gel coating is the simplest method for metal oxide compound deposition onto the substrate 2. The second part focuses on testing the used modification and chosen substrates. This study aims to prevent bacterial adhesion with surface thus modification is carried out. FTIR analysis was applied, to observe changes on modified textile surface. Pre and post modification changes in comfort properties also must be taken into account. Air permeability was tested. Modification with silica-based coating with zinc acetate dihydrate was applied onto polyamide, cotton textile and yarns to ensure antibacterial activity. Antibacterial activity was tested against Bacillus subtilis mscL 1141 and Staphylococcus aurerus mscL 334.