The Use of Sulfonyl Group Dance in Synthesis of 6-Azido-2-Sulfonyl Purine Derivatives

Paul Walden 11th Symposium on Organic Chemistry: Program and Abstract book 2019
Jānis Miķelis Zaķis, Kristers Ozols

Here we report a new approach for synthesis of 6-azido-2-sulfonyl purine derivatives. The transformation from can be explained by azido-tetrazolo tautomerism. The latter activates purine cycle towards SNAr reaction at otherwise less reactive C2.

Keywords
Purine derivatives, SNAr reactions, tetrazole

Zaķis, J., Ozols, K. The Use of Sulfonyl Group Dance in Synthesis of 6-Azido-2-Sulfonyl Purine Derivatives. In: Paul Walden 11th Symposium on Organic Chemistry: Program and Abstract book, Latvia, Rīga, 19-20 September, 2019. Rīga: 2019, pp.54-54.

Publication language
English (en)