This work deals with the electrically conductive textiles for heat generation in orthopedic compression supports. This study aimed to develop compression knitted structures with integrated electro-conductive yarns and investigate their heat generation characteristics and temperature changes during the time and under stretch which is required to generate compression. Combined half-Milano rib structured knitted fabrics were made by using silver (Ag) coated PA yarn of linear density of 66 tex and 235 tex, respectively. Six variants of specimens were developed by using different amount of electro-conductive yarns in a pattern repeat. It was found that stretch negatively influences temperature values as well as time in which the required temperature is reached. Therefore, the final wearing conditions have to be summed up during the designing of compression orthopedic heated supports.