Optical frequency combs (OFCs) generated in microresonators with whispering gallery modes are demanded for different applications including telecommunications. Extending operating spectral ranges is an important problem for wavelength-division multiplexing systems based on microresonators. We demonstrate experimentally three spectrally separated OFCs in the C-, U-, and E-bands in silica microspheres which, in principle, can be used for telecommunication ap-plications. For qualitative explanation of the OFC generation in the sidebands, we calculated gain coefficients and gain bandwidths for degenerate four-wave mixing (FWM) processes. We also attained a regime when the pump frequency was in the normal dispersion range and only two OFCs were generated. The first OFC was near the pump frequency and the second Ra-man-assisted OFC with a soliton-like spectrum was in the U-band. Numerical simulation based on the Lugiato–Lefever equation was performed to support this result and demonstrate that the Raman-assisted OFC may be a soliton.