Sulfur Dioxide Promoted Glycosylation with Glycosyl Fluorides

Riga Technical University 62nd International Scientific Conference "Materials Science and Applied Chemistry": Program and Abstracts 2021
Krista Gulbe, Jevgeņija Lugiņina, Edijs Jansons, Artis Kinēns, Māris Turks

Liquid SO2 is a polar solvent that possesses Lewis acid properties. It is known to facilitate Lewis acid promoted and/or carbenium ion mediated chemical transformations. Apart from that, SO2 has an affinity towards fluoride ion that leads to covalent bonding in the form of relatively stable fluorosulfite anion. Based on the aforementioned physico-chemical properties of SO2, we have developed sulfur dioxide-promoted glycosylation with glycosyl fluorides as glycosyl donors in liquid SO2 without an external promoter.

Keywords
sulfur dioxide, glycosyl fluoride, glycosylation
Hyperlink
https://msac.rtu.lv/wp-content/uploads/sites/18/2021/11/MSAC-2021-VISAS-kopa.pdf

Gulbe, K., Lugiņina, J., Jansons, E., Kinēns, A., Turks, M. Sulfur Dioxide Promoted Glycosylation with Glycosyl Fluorides. In: Riga Technical University 62nd International Scientific Conference "Materials Science and Applied Chemistry": Program and Abstracts, Latvia, Riga, 22-22 October, 2021. Riga: Riga Technical University, 2021, pp.25-25.

Publication language
English (en)