Metal-Free Sulfur Dioxide-Assisted Glycosylation with Glycosyl Fluorides

27th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts 2021
Krista Gulbe, Jevgeņija Lugiņina, Edijs Jansons, Artis Kinēns, Māris Turks

Liquid SO2 is a polar solvent that possesses Lewis acid properties. It is known to facilitate Lewis acid promoted and/or carbenium ion mediated chemical transformations. Apart from that, SO2 has an affinity towards fluoride ion that leads to covalent bonding in the form of relatively stable fluorosulfite anion. Based on the aforementioned physico-chemical properties of SO2, we have developed sulfur dioxide-assisted glycosylation with glycosyl fluorides as glycosyl donors in liquid SO2 without an external promoter.

Keywords
sulfur dioxide, glycosyl fluoride, glycosylation
Hyperlink
https://27hskiki.hkd.hr/book-of-abstracts/

Gulbe, K., Lugiņina, J., Jansons, E., Kinēns, A., Turks, M. Metal-Free Sulfur Dioxide-Assisted Glycosylation with Glycosyl Fluorides. In: 27th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts, Croatia, Veli Lošinj, 5-8 October, 2021. Zagreb: Croatian Chemical Society, 2021, pp.120-120. e-ISSN 2757-0754.

Publication language
English (en)