Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group

ACS Omega 2022
Konstantinos Grammatoglou, Madara Dārziņa, Aigars Jirgensons

6-Methylpyridyl-2-methyl protected tetrazoles can be C-H deprotonated using the turbo-Grignard reagent and involved in the reactions with aldehydes and ketones. The protecting group can be cleaved under reductive electrochemical conditions using Pb bronze as a cathode and Zn as a sacrificial anode.

DOI
10.1021/acsomega.2c01633
Hyperlink
https://pubs.acs.org/doi/10.1021/acsomega.2c01633

Grammatoglou, K., Dārziņa, M., Jirgensons, A. Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group. ACS Omega, 2022, Vol. 7, No. 21, pp.18103-18109. ISSN 2470-1343. Available from: doi:10.1021/acsomega.2c01633

Publication language
English (en)