RTU Research Information System
Latviešu English

Publikācija: Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts

Publication Type Full-text conference paper published in other conference proceedings
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts
Field of research 1. Natural sciences
Sub-field of research 1.3 Physical sciences
Authors Jurijs Dehtjars
Nataļja Poļaka
Rachel Sammons
Keywords implant, hydroxyapatite, electrical charge, immobilisation, proliferation
Abstract Hydroxyapatite (HAP) is in use to fabricate implants in dentistry and orthopaedy. To functionalise a surface of the HAP that has a direct contact to the human cells a surface electrical charge deposition is employed. The current technologies can not provide uniformity of the charge for contrarily situated surfaces. To overcome such the disadvantage a HAP hydrogenation technology has been reached. As the result the surface charge has been engineered. The charge was estimated owing to measurements of the photoelectron emission work function. The later was increased to ∼ 0.2 eV. The negatively charged HAP surface in contrast with the uncharged one attached 10 times more osteoblatic cells and increased their proliferation capacity in 1.6 time
DOI: 10.1007/978-3-540-69367-3_7
Hyperlink: http://link.springer.com/chapter/10.1007/978-3-540-69367-3_7 
Reference Dehtjars, J., Poļaka, N., Sammons, R. Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts. In: IFMBE Proceedings. Vol.20: 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC 2008), Latvia, Rīga, 16-20 June, 2008. Berlin: Springer Berlin Heidelberg, 2008, pp.23-25. ISBN 9783540693666.
ID 3589