Development of Malarial Enzyme Inhibitors

2023
Elīna Līdumniece

Defending
25.05.2023. 14:00, Materiālzinātnes un lietišķās ķīmijas fakultātē, Rīgā, Paula Valdena ielā 3, 272. auditorijā

Supervisor
Aigars Jirgensons

Reviewers
Pavels Arsenjans, Māra Plotniece, Gabriele Costantino

The research presented in the Thesis describes the development of synthesis methods to obtain peptidic boronic acid SUB1 inhibitors. The established synthetic routes enabled an access of various peptidic boronic acids with modified P1, P3 and P5 positions.

Keywords
Malaria, Peptidic boronic acids, α-Ketoamides, SUB1 inhibitors
DOI
10.7250/9789934229107

Līdumniece, Elīna. Development of Malarial Enzyme Inhibitors. PhD Thesis. Rīga: [RTU], 2023. 148 p.

Publication language
English (en)