Injectable Platelet-Rich Fibrin as a Drug Carrier Increases the Antibacterial Susceptibility of Antibiotic-Clindamycin Phosphate

Bioinspiration in Biomaterials: 16th Scandinavian Society for Biomaterials Meeting (ScSB 2023) 2023
Karina Egle, Ingus Skadiņš, Andra Grava, Lana Mičko, Viktors Dubņiks, Ilze Šalma, Arita Dubņika

Platelet-rich fibrin (PRF) is an autogenous material derived from human blood and is widely used to promote wound healing and tissue regeneration [1]. Clindamycin phosphate (CLP) is a prodrug of clindamycin that has no antibacterial activity [2]. The aim of this study was to investigate the change in CLP antibacterial properties against reference culture and clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis using platelet-rich fibrin as a carrier matrix.

Keywords
platelet-rich fibrin, antibacterial tests

Egle, K., Skadiņš, I., Grava, A., Mičko, L., Dubņiks, V., Šalma, I., Dubņika, A. Injectable Platelet-Rich Fibrin as a Drug Carrier Increases the Antibacterial Susceptibility of Antibiotic-Clindamycin Phosphate. In: Bioinspiration in Biomaterials: 16th Scandinavian Society for Biomaterials Meeting (ScSB 2023), Norway, Roros, 21-24 March, 2023. Roros: 2023, pp.57-57.

Publication language
English (en)