The paper proposes a methodology for designing intelligent systems of autonomous distributed hybrid power complexes (ADHPC) ensuring a minimum level of energy consumption from the national external grid as well as diesel power plants used to deliver the power to regional households, and industrial consumers. It will be realized because of the effective use of generated energy from renewable energy sources in such ADHPC systems by considering their both normal and emergency operating modes. In doing so, ADHPC will not only help offload the existing power grid during peak demand, but also allow for significant process efficiencies in energy production from renewable energy sources (RES), including “green” hydrogen: for instance, the excess energy is accumulated during the period of its excess and is provided back to power consumers in the period of shortage, the electricity losses are reduced since effective management is applied for power flows circulating in the ADHPC systems. The methodology includes the following stages (subtasks): development of the structure of a distributed hybrid system for generating and transporting electricity from sources to consumers; development of a system for diagnostics of failures of generating units and wire breaks in sections of local power transportation networks and management based on the diagnostics results of power flows circulating in the ADHPC systems for both normal and emergency modes. Therefore, a balance of power capacities and minimization of their losses are ensured.