C-H Arylation of Pentacyclic Triterpenoids

Latvijas Universitātes 81. zinātniskā konference. Ķīmijas sekcija: tēžu krājums 2023
Vladislavs Kroškins, Jevgeņija Lugiņina, Māris Turks

Naturally abundant pentacyclic triterpenoids are significant secondary metabolites which have aroused huge interest by possessing wide range of remarkable biological activities such as antitumor[1] antidiabetic [2] anti-inflammatory [3] and antiviral activities [4]. Oleanolic, ursolic acids and betulin, are the most recognizable compounds of this branch, which are isolated from various plants. The aim of this work is to obtain novel triterpenoic derivatives by C-H arylation at C(22). For this purpose, precursors bearing picolinic amide directing groups were synthesized

Keywords
C-H activation, pentacyclic triterpenoids
Hyperlink
https://conferences.lu.lv/event/245/attachments/266/763/Organic%20chemistry%20session%20abstracts%202023.pdf

Kroškins, V., Lugiņina, J., Turks, M. C-H Arylation of Pentacyclic Triterpenoids. In: Latvijas Universitātes 81. zinātniskā konference. Ķīmijas sekcija: tēžu krājums, Latvia, Rīga, 17-17 May, 2023. Rīga: 2023, pp.11-11.

Publication language
English (en)